STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C1QTNF12C1q and TNF related 12. (295 aa)    
Predicted Functional Partners:
UBE2V1
TMEM189_B_dmain domain-containing protein.
   
 
 0.943
UBE2G2
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.798
ATG7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
   
 0.780
UBE2H
Ubiquitin-conjugating enzyme E2 H isoform 1; Belongs to the ubiquitin-conjugating enzyme family.
     
 0.746
MARCHF6
Membrane associated ring-CH-type finger 6.
    
 
 0.704
UBE2S
Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.699
UBE2W
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.689
UBA3
NEDD8-activating enzyme E1 catalytic subunit isoform 1.
   
 0.681
UBA5
Ubiquitin like modifier activating enzyme 5.
   
 0.672
UBE2K
Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.668
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.