STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO1Shugoshin 1. (554 aa)    
Predicted Functional Partners:
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.947
CDCA8
Cell division cycle associated 8.
   
 0.941
SGO2
Shugoshin 2.
  
  
 0.932
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
 0.908
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.902
PLK1
Serine/threonine-protein kinase PLK.
   
 0.889
HJURP
Holliday junction recognition protein.
   
  
 0.889
ESPL1
Extra spindle pole bodies like 1, separase.
   
 
 0.885
CDC20
Cell division cycle protein 20 homolog.
   
 0.883
PPP2R1A
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform.
    
 
 0.873
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.