SDHC protein (Macaca mulatta) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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filled nodes:
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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

SDHC

Uncharacterized protein. (176 aa)

Predicted Functional Partners:

SDHB

0.998

SDHD

0.997

SDHA

0.997

SUCLG1

0.990

FH

0.984

SDHD-2

0.980

SUCLA2

0.979

SUCLG2

0.976

LOC723069

0.956

ENSMMUP00000076876

0.935

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMMUP00000076876	FH	ENSMMUP00000076876	ENSMMUP00000007489	2Fe-2S ferredoxin-type domain-containing protein.	Fumarate hydratase, mitochondrial.	0.908
ENSMMUP00000076876	LOC723069	ENSMMUP00000076876	ENSMMUP00000048667	2Fe-2S ferredoxin-type domain-containing protein.	Succ_DH_flav_C domain-containing protein.	0.981
ENSMMUP00000076876	SDHA	ENSMMUP00000076876	ENSMMUP00000053637	2Fe-2S ferredoxin-type domain-containing protein.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.980
ENSMMUP00000076876	SDHC	ENSMMUP00000076876	ENSMMUP00000038519	2Fe-2S ferredoxin-type domain-containing protein.	Uncharacterized protein.	0.935
ENSMMUP00000076876	SDHD	ENSMMUP00000076876	ENSMMUP00000019985	2Fe-2S ferredoxin-type domain-containing protein.	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family.	0.961
ENSMMUP00000076876	SDHD-2	ENSMMUP00000076876	ENSMMUP00000065248	2Fe-2S ferredoxin-type domain-containing protein.	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family.	0.961
ENSMMUP00000076876	SUCLA2	ENSMMUP00000076876	ENSMMUP00000011412	2Fe-2S ferredoxin-type domain-containing protein.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.890
ENSMMUP00000076876	SUCLG1	ENSMMUP00000076876	ENSMMUP00000001216	2Fe-2S ferredoxin-type domain-containing protein.	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	0.961
ENSMMUP00000076876	SUCLG2	ENSMMUP00000076876	ENSMMUP00000074896	2Fe-2S ferredoxin-type domain-containing protein.	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.812
FH	ENSMMUP00000076876	ENSMMUP00000007489	ENSMMUP00000076876	Fumarate hydratase, mitochondrial.	2Fe-2S ferredoxin-type domain-containing protein.	0.908
FH	LOC723069	ENSMMUP00000007489	ENSMMUP00000048667	Fumarate hydratase, mitochondrial.	Succ_DH_flav_C domain-containing protein.	0.959
FH	SDHA	ENSMMUP00000007489	ENSMMUP00000053637	Fumarate hydratase, mitochondrial.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.998
FH	SDHB	ENSMMUP00000007489	ENSMMUP00000002161	Fumarate hydratase, mitochondrial.	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.990
FH	SDHC	ENSMMUP00000007489	ENSMMUP00000038519	Fumarate hydratase, mitochondrial.	Uncharacterized protein.	0.984
FH	SDHD	ENSMMUP00000007489	ENSMMUP00000019985	Fumarate hydratase, mitochondrial.	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family.	0.978
FH	SDHD-2	ENSMMUP00000007489	ENSMMUP00000065248	Fumarate hydratase, mitochondrial.	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family.	0.790
FH	SUCLA2	ENSMMUP00000007489	ENSMMUP00000011412	Fumarate hydratase, mitochondrial.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.863
FH	SUCLG1	ENSMMUP00000007489	ENSMMUP00000001216	Fumarate hydratase, mitochondrial.	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	0.921
FH	SUCLG2	ENSMMUP00000007489	ENSMMUP00000074896	Fumarate hydratase, mitochondrial.	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.722
LOC723069	ENSMMUP00000076876	ENSMMUP00000048667	ENSMMUP00000076876	Succ_DH_flav_C domain-containing protein.	2Fe-2S ferredoxin-type domain-containing protein.	0.981