STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN22Protein tyrosine phosphatase non-receptor type 22. (813 aa)    
Predicted Functional Partners:
CSK
Tyrosine-protein kinase.
   
 0.938
PSTPIP1
Proline-serine-threonine phosphatase interacting protein 1.
   
 
 0.881
SHC1
SHC-transforming protein 1 isoform 3.
   
 0.729
MATK
Tyrosine-protein kinase.
   
 0.717
RFX5
DNA-binding protein RFX5.
   
  
 0.673
ZAP70
Tyrosine-protein kinase.
   
 0.664
GDE1
Glycerophosphodiester phosphodiesterase 1.
   
  
 0.654
SHC3
Uncharacterized protein.
   
 0.635
NAPEPLD
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D.
      
 0.617
LCK
Tyrosine-protein kinase.
   
 0.616
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.