MEF2C protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GATA4	MEF2A	ENSMMUP00000025244	ENSMMUP00000054321	GATA binding protein 4.	Myocyte-specific enhancer factor 2A isoform 2.	0.579
GATA4	MEF2C	ENSMMUP00000025244	ENSMMUP00000042872	GATA binding protein 4.	Myocyte-specific enhancer factor 2C isoform 1.	0.929
GATA4	MEF2D	ENSMMUP00000025244	ENSMMUP00000021952	GATA binding protein 4.	Myocyte-specific enhancer factor 2D.	0.546
GATA4	NFATC1	ENSMMUP00000025244	ENSMMUP00000080336	GATA binding protein 4.	Nuclear factor of activated T cells 1.	0.912
GATA4	NFATC4	ENSMMUP00000025244	ENSMMUP00000060544	GATA binding protein 4.	Nuclear factor of activated T cells 4.	0.927
GATA4	NKX2-5	ENSMMUP00000025244	ENSMMUP00000072700	GATA binding protein 4.	NK2 homeobox 5.	0.989
HDAC4	MEF2A	ENSMMUP00000007984	ENSMMUP00000054321	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myocyte-specific enhancer factor 2A isoform 2.	0.857
HDAC4	MEF2C	ENSMMUP00000007984	ENSMMUP00000042872	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myocyte-specific enhancer factor 2C isoform 1.	0.952
HDAC4	MEF2D	ENSMMUP00000007984	ENSMMUP00000021952	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myocyte-specific enhancer factor 2D.	0.854
MAPK11	MAPK13	ENSMMUP00000018541	ENSMMUP00000045645	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.975
MAPK11	MAPK14	ENSMMUP00000018541	ENSMMUP00000011075	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.977
MAPK11	MEF2A	ENSMMUP00000018541	ENSMMUP00000054321	Mitogen-activated protein kinase.	Myocyte-specific enhancer factor 2A isoform 2.	0.839
MAPK11	MEF2C	ENSMMUP00000018541	ENSMMUP00000042872	Mitogen-activated protein kinase.	Myocyte-specific enhancer factor 2C isoform 1.	0.972
MAPK11	MEF2D	ENSMMUP00000018541	ENSMMUP00000021952	Mitogen-activated protein kinase.	Myocyte-specific enhancer factor 2D.	0.624
MAPK13	MAPK11	ENSMMUP00000045645	ENSMMUP00000018541	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.975
MAPK13	MAPK14	ENSMMUP00000045645	ENSMMUP00000011075	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.985
MAPK13	MEF2A	ENSMMUP00000045645	ENSMMUP00000054321	Mitogen-activated protein kinase.	Myocyte-specific enhancer factor 2A isoform 2.	0.703
MAPK13	MEF2C	ENSMMUP00000045645	ENSMMUP00000042872	Mitogen-activated protein kinase.	Myocyte-specific enhancer factor 2C isoform 1.	0.966
MAPK13	MEF2D	ENSMMUP00000045645	ENSMMUP00000021952	Mitogen-activated protein kinase.	Myocyte-specific enhancer factor 2D.	0.613
MAPK14	MAPK11	ENSMMUP00000011075	ENSMMUP00000018541	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.977