STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLCO2A1Solute carrier organic anion transporter family member. (643 aa)    
Predicted Functional Partners:
FMO4
Dimethylaniline monooxygenase [N-oxide-forming].
   
  
 0.755
FMO1
Dimethylaniline monooxygenase [N-oxide-forming].
   
  
 0.735
FMO5
Dimethylaniline monooxygenase [N-oxide-forming].
   
  
 0.718
FMO3
Dimethylaniline monooxygenase [N-oxide-forming] 3; Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thr [...]
   
  
 0.714
SLC22A2
Solute carrier family 22 member 2.
   
  
 0.604
SLC22A23
Solute carrier family 22 member 23.
   
  
 0.592
SLC22A5
Solute carrier family 22 member 5.
   
  
 0.589
SLC22A17
Solute carrier family 22 member 17 isoform a.
   
  
 0.587
ABCC4
ATP binding cassette subfamily C member 4.
      
 0.584
HPGD
15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  
 0.544
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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