STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (2207 aa)    
Predicted Functional Partners:
ELMO1
Engulfment and cell motility protein 1 isoform 1.
    
 0.852
CRK
CRK proto-oncogene, adaptor protein.
    
 0.840
USP40
Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family.
      
 0.780
RHOG
Rho-related GTP-binding protein RhoG.
   
 0.748
ELMO3
Engulfment and cell motility 3.
    
 0.738
ELMO2
Engulfment and cell motility 2.
    
 0.702
LRRC2
Leucine rich repeat containing 2.
      
 0.688
ABI1
Abl interactor 1 isoform a.
     
 0.681
CDC42
Cell division control protein 42 homolog isoform 1.
   
 0.679
NEDD9
Neural precursor cell expressed, developmentally down-regulated 9.
    
 0.652
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.