node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BDNF | GDNF | ENSMMUP00000059263 | ENSMMUP00000024951 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Glial cell derived neurotrophic factor. | 0.954 |
BDNF | IGF1R | ENSMMUP00000059263 | ENSMMUP00000016141 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Tyrosine-protein kinase receptor. | 0.824 |
BDNF | NGF | ENSMMUP00000059263 | ENSMMUP00000046298 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Nerve growth factor; Belongs to the NGF-beta family. | 0.910 |
BDNF | NGFR | ENSMMUP00000059263 | ENSMMUP00000019165 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Nerve growth factor receptor. | 0.907 |
BDNF | NRTN | ENSMMUP00000059263 | ENSMMUP00000065757 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Neurturin preproprotein. | 0.711 |
BDNF | NTRK1 | ENSMMUP00000059263 | ENSMMUP00000016316 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Tyrosine-protein kinase receptor. | 0.945 |
BDNF | NTRK2 | ENSMMUP00000059263 | ENSMMUP00000073592 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Tyrosine-protein kinase receptor. | 0.996 |
BDNF | NTRK3 | ENSMMUP00000059263 | ENSMMUP00000047448 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Tyrosine-protein kinase receptor. | 0.884 |
BDNF | SORCS2 | ENSMMUP00000059263 | ENSMMUP00000029504 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Sortilin related VPS10 domain containing receptor 2. | 0.565 |
BDNF | SORT1 | ENSMMUP00000059263 | ENSMMUP00000052188 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Sortilin. | 0.928 |
GDNF | BDNF | ENSMMUP00000024951 | ENSMMUP00000059263 | Glial cell derived neurotrophic factor. | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | 0.954 |
GDNF | NGF | ENSMMUP00000024951 | ENSMMUP00000046298 | Glial cell derived neurotrophic factor. | Nerve growth factor; Belongs to the NGF-beta family. | 0.859 |
GDNF | NRTN | ENSMMUP00000024951 | ENSMMUP00000065757 | Glial cell derived neurotrophic factor. | Neurturin preproprotein. | 0.648 |
GDNF | NTRK1 | ENSMMUP00000024951 | ENSMMUP00000016316 | Glial cell derived neurotrophic factor. | Tyrosine-protein kinase receptor. | 0.667 |
GDNF | NTRK2 | ENSMMUP00000024951 | ENSMMUP00000073592 | Glial cell derived neurotrophic factor. | Tyrosine-protein kinase receptor. | 0.669 |
GDNF | NTRK3 | ENSMMUP00000024951 | ENSMMUP00000047448 | Glial cell derived neurotrophic factor. | Tyrosine-protein kinase receptor. | 0.659 |
IGF1R | BDNF | ENSMMUP00000016141 | ENSMMUP00000059263 | Tyrosine-protein kinase receptor. | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | 0.824 |
IGF1R | NGF | ENSMMUP00000016141 | ENSMMUP00000046298 | Tyrosine-protein kinase receptor. | Nerve growth factor; Belongs to the NGF-beta family. | 0.783 |
NGF | BDNF | ENSMMUP00000046298 | ENSMMUP00000059263 | Nerve growth factor; Belongs to the NGF-beta family. | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | 0.910 |
NGF | GDNF | ENSMMUP00000046298 | ENSMMUP00000024951 | Nerve growth factor; Belongs to the NGF-beta family. | Glial cell derived neurotrophic factor. | 0.859 |