STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PROCVitamin K-dependent protein C; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. (483 aa)    
Predicted Functional Partners:
THBD
Uncharacterized protein.
    
 0.989
F5
Coagulation factor V; Belongs to the multicopper oxidase family.
    
 0.985
F8
Coagulation factor VIII; Belongs to the multicopper oxidase family.
    
 0.977
PROCR
Protein C receptor.
    
 0.969
SERPINA5
SERPIN domain-containing protein; Belongs to the serpin family.
   
 0.964
F2
Coagulation factor II, thrombin; Belongs to the peptidase S1 family.
  
0.960
F2R
Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.955
SERPINA1
SERPIN domain-containing protein; Belongs to the serpin family.
   
 0.942
SERPINE1
Serpin family E member 1; Belongs to the serpin family.
    
 0.940
SERPINB2
Serpin family B member 2; Belongs to the serpin family.
   
 0.928
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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