STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDR1WD repeat domain 1. (609 aa)    
Predicted Functional Partners:
SMCR8
SMCR8-C9orf72 complex subunit.
      
 0.870
CAPZB
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.861
CFL1
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 
 0.843
CFL2
Cofilin-2; Belongs to the actin-binding proteins ADF family.
   
 
 0.833
ZNF518B
Zinc finger protein 518B.
      
 0.826
ACTR3
Actin-related protein 3; Belongs to the actin family.
   
 0.752
ACTR3B
Actin-related protein 3B isoform 1; Belongs to the actin family.
   
 0.744
CAP1
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 
 0.700
SLC2A9
Solute carrier family 2 member 9; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
 
    
 0.698
DSTN
Destrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family.
   
 
 0.694
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.