STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COX5ACytochrome c oxidase subunit 5A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (150 aa)    
Predicted Functional Partners:
COX7C
Cytochrome c oxidase subunit 7C.
   
 0.999
COX6C
Cytochrome c oxidase subunit 6C proprotein.
   
 0.999
COX5B
Cytochrome c oxidase subunit 5B.
   
 0.999
COX4I1
Uncharacterized protein.
   
 0.999
CYC1
Cytochrome c1.
   
 0.998
UQCRQ
Cytochrome b-c1 complex subunit 8.
   
 0.998
LOC701223
Uncharacterized protein.
   
 0.997
COX6B1
Cytochrome c oxidase subunit 6B1; Connects the two COX monomers into the physiological dimeric form.
   
 0.995
COX4I2
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial.
   
 0.995
ENSMMUP00000053635
Uncharacterized protein.
   
 0.994
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.