STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLK2Serine/threonine-protein kinase PLK. (685 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.893
ESPL1
Extra spindle pole bodies like 1, separase.
   
 0.862
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
 0.822
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.812
KIF23
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.811
SMC3
Structural maintenance of chromosomes protein.
   
 0.802
RAD21L1
RAD21 cohesin complex component like 1.
   
 0.797
RAD21
Double-strand-break repair protein rad21 homolog.
   
 0.797
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.796
INCENP
Inner centromere protein.
   
 0.780
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.