STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TULP4TUB like protein 4. (1554 aa)    
Predicted Functional Partners:
PCNP
PEST proteolytic signal-containing nuclear protein.
      
 0.864
KLHL2
Kelch like family member 2.
     
 0.837
KCNE4
Potassium voltage-gated channel subfamily E regulatory subunit 4.
      
 0.807
BCAR3
BCAR3 adaptor protein, NSP family member.
     
 0.804
UBE3C
Ubiquitin-protein ligase E3C.
      
 0.696
RIMS2
Regulating synaptic membrane exocytosis 2.
      
 0.695
CUL5
Cullin 5; Belongs to the cullin family.
    
 0.685
MYCBP2
MYC binding protein 2.
      
 0.673
RAB3B
RAB3B, member RAS oncogene family.
   
  
 0.659
CRHR1
Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to st [...]
      
 0.659
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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