RELA protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHUK	IKBKB	ENSMMUP00000043850	ENSMMUP00000032125	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1.	0.999
CHUK	IKBKG	ENSMMUP00000043850	ENSMMUP00000040739	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.999
CHUK	NFKB1	ENSMMUP00000043850	ENSMMUP00000034946	Component of inhibitor of nuclear factor kappa B kinase complex.	Uncharacterized protein.	0.998
CHUK	NFKB2	ENSMMUP00000043850	ENSMMUP00000003997	Component of inhibitor of nuclear factor kappa B kinase complex.	Nuclear factor kappa B subunit 2.	0.996
CHUK	NFKBIA	ENSMMUP00000043850	ENSMMUP00000054148	Component of inhibitor of nuclear factor kappa B kinase complex.	NF-kappa-B inhibitor alpha.	0.999
CHUK	NFKBIB	ENSMMUP00000043850	ENSMMUP00000031129	Component of inhibitor of nuclear factor kappa B kinase complex.	NF-kappa-B inhibitor beta isoform a.	0.997
CHUK	NFKBIE	ENSMMUP00000043850	ENSMMUP00000029868	Component of inhibitor of nuclear factor kappa B kinase complex.	NFKB inhibitor epsilon.	0.970
CHUK	RELA	ENSMMUP00000043850	ENSMMUP00000054901	Component of inhibitor of nuclear factor kappa B kinase complex.	RELA proto-oncogene, NF-kB subunit.	0.998
CHUK	RELB	ENSMMUP00000043850	ENSMMUP00000018596	Component of inhibitor of nuclear factor kappa B kinase complex.	RELB proto-oncogene, NF-kB subunit.	0.992
CHUK	TNF	ENSMMUP00000043850	ENSMMUP00000056761	Component of inhibitor of nuclear factor kappa B kinase complex.	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	0.974
IKBKB	CHUK	ENSMMUP00000032125	ENSMMUP00000043850	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.999
IKBKB	IKBKG	ENSMMUP00000032125	ENSMMUP00000040739	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.999
IKBKB	NFKB1	ENSMMUP00000032125	ENSMMUP00000034946	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1.	Uncharacterized protein.	0.998
IKBKB	NFKB2	ENSMMUP00000032125	ENSMMUP00000003997	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1.	Nuclear factor kappa B subunit 2.	0.928
IKBKB	NFKBIA	ENSMMUP00000032125	ENSMMUP00000054148	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1.	NF-kappa-B inhibitor alpha.	0.999
IKBKB	NFKBIB	ENSMMUP00000032125	ENSMMUP00000031129	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1.	NF-kappa-B inhibitor beta isoform a.	0.992
IKBKB	NFKBIE	ENSMMUP00000032125	ENSMMUP00000029868	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1.	NFKB inhibitor epsilon.	0.967
IKBKB	RELA	ENSMMUP00000032125	ENSMMUP00000054901	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1.	RELA proto-oncogene, NF-kB subunit.	0.997
IKBKB	RELB	ENSMMUP00000032125	ENSMMUP00000018596	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1.	RELB proto-oncogene, NF-kB subunit.	0.876
IKBKB	TNF	ENSMMUP00000032125	ENSMMUP00000056761	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1.	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	0.974