STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RIOK3Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (519 aa)    
Predicted Functional Partners:
RIOK2
Serine/threonine-protein kinase RIO2 isoform 1.
   
 
 0.972
NOB1
RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family.
   
 0.950
LTV1
LTV1 ribosome biogenesis factor.
   
 0.927
TSR1
TSR1 ribosome maturation factor.
   
 0.889
BYSL
Bystin like.
   
 0.885
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
  0.863
RPS3
40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
   
 0.852
LOC703455
40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3.
    
 0.797
RPS21
40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family.
    
 0.787
LOC712274
40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
   
  0.783
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.