STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB123Beta-defensin 123; Has antibacterial activity. (67 aa)    
Predicted Functional Partners:
DEFB119
Macaca mulatta defensin, beta 119 (DEFB119), mRNA.
   
 
 0.932
DEFB115
Defensin, beta 115.
     
 0.517
DEFB1
Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
     
 0.502
LOC694235
Defensin, beta 103.
   
 
 0.492
DEFB125
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.482
DEFB130B
Uncharacterized protein.
     
 0.454
LOC693962
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
   
 
 0.439
DEFB108B
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.427
DEFB135
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.426
DEFB113
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.421
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.