STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTHLHParathyroid hormone-related protein isoform 1 preproprotein. (177 aa)    
Predicted Functional Partners:
PTH1R
Parathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family.
    
 0.994
PTH2R
Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family.
    
 0.836
KPNB1
Karyopherin subunit beta 1.
    
 
 0.827
PTH
Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.
     
 0.808
SCTR
Secretin receptor; Belongs to the G-protein coupled receptor 2 family.
    
 0.673
LOC694289
Uncharacterized protein.
    
 0.638
GHRHR
Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.
    
 0.632
CAP2
Adenylyl cyclase-associated protein; Belongs to the CAP family.
      
 0.628
LRRC38
Leucine rich repeat containing 38.
      
 0.628
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
  
 0.608
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.