STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NFIXNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (586 aa)    
Predicted Functional Partners:
RANBP3
Ran-binding protein 3 isoform RANBP3-a.
   
  
 0.812
NF1
Neurofibromin 1.
   
  
 0.781
GATA4
GATA binding protein 4.
    
 
 0.694
GATA6
Transcription factor GATA-6.
    
 
 0.691
SULT2A1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.651
USF2
BHLH domain-containing protein.
      
 0.651
HSD3B1
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; Belongs to the 3-beta-HSD family.
      
 0.638
POR
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
      
 0.638
KDM6B
Lysine demethylase 6B.
    
 
 0.628
FXR2
Uncharacterized protein.
      
 0.596
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.