STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHANK2SH3 and multiple ankyrin repeat domains 2. (1846 aa)    
Predicted Functional Partners:
SHANK3
SH3 and multiple ankyrin repeat domains 3.
    
0.951
SHANK1
SH3 and multiple ankyrin repeat domains 1.
    
0.943
DLGAP2
DLG associated protein 2.
    
 0.864
NLGN3
Neuroligin-3; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity).
    
 0.855
DLGAP1
Disks large-associated protein 1 isoform 1.
    
 0.836
NRXN1
Uncharacterized protein.
   
 
 0.833
DLG4
Uncharacterized protein; Belongs to the MAGUK family.
   
 0.814
DLGAP4
Disks large-associated protein 4 isoform a.
    
 0.794
DLGAP3
Disks large-associated protein 3.
    
 0.767
CTTN
SH3 domain-containing protein.
    
 
 0.724
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.