STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRSS27Serine protease 27; Belongs to the peptidase S1 family. (291 aa)    
Predicted Functional Partners:
DMBT1
Uncharacterized protein.
 
  
  0.760
LPA
Apolipoprotein(a); Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330.
 
 
 
  0.640
LIPE
Lipase E, hormone sensitive type.
   
 0.555
ABHD17B
Abhydrolase domain-containing protein FAM108B1 isoform 1.
      
 0.535
TPP2
Tripeptidyl peptidase 2.
   
 
 0.514
MST1R
Macrophage stimulating 1 receptor.
    
 0.504
MET
Uncharacterized protein.
    
 0.504
LYPLA2
Acyl-protein thioesterase 2.
   
 
 0.494
AFMID
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
   
 0.492
PRCP
Uncharacterized protein.
   
 
 0.484
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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