STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DPPA5Developmental pluripotency associated 5. (116 aa)    
Predicted Functional Partners:
KHDC1
KH homology domain-containing protein 1 isoform 2.
      
 0.855
COX14
Stella-related protein.
   
  
 0.776
DPPA3
Uncharacterized protein.
   
  
 0.776
KLF17
Kruppel like factor 17.
      
 0.686
NANOG
Nanog homeobox.
   
  
 0.602
TFCP2L1
Transcription factor CP2 like 1.
      
 0.556
POU5F1
POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency; Belongs to the POU transcription factor family. Class-5 subfamily.
   
  
 0.554
DNMT3L
DNA (Cytosine-5)-methyltransferase 3-like protein.
   
  
 0.543
CLDN4
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.537
KHDC1L
KH domain containing 1 like.
      
 0.528
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.