STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3660 aa)    
Predicted Functional Partners:
UPF1
UPF1 RNA helicase and ATPase.
   
 0.998
UPF2
UPF2 regulator of nonsense mediated mRNA decay.
   
 
 0.996
SMG7
SMG7 nonsense mediated mRNA decay factor.
   
 0.992
SMG9
Uncharacterized protein.
    
 0.969
SMG8
Protein SMG8.
   
 0.969
ETF1
Eukaryotic peptide chain release factor subunit 1.
    
 
 0.968
EIF4A3
Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family.
   
 0.959
SMG5
SMG5 nonsense mediated mRNA decay factor.
   
 0.958
RPTOR
Regulatory associated protein of MTOR complex 1.
   
 0.956
RICTOR
RPTOR independent companion of MTOR complex 2.
   
 0.955
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.