STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC714190Uncharacterized protein. (442 aa)    
Predicted Functional Partners:
CD226
CD226 antigen; Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T- lymphocyte (CTL) and NK cell. Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding.
   
 0.996
TIGIT
T cell immunoreceptor with Ig and ITIM domains.
    
 0.988
PVR
Uncharacterized protein.
  
 
 
0.901
CD96
CD96 molecule.
    
 0.894
TOMM22
Mitochondrial import receptor subunit TOM22 homolog.
   
 0.829
TOMM7
Mitochondrial import receptor subunit TOM7 homolog.
    
 0.815
SCARB2
Scavenger receptor class B member 2; Belongs to the CD36 family.
      
 0.795
ZNF395
C2H2-type domain-containing protein.
   
 0.748
SAMM50
SAMM50 sorting and assembly machinery component.
    
 0.729
NECTIN3
Nectin cell adhesion molecule 3.
    
0.728
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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