STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSFX3HSF_DOMAIN domain-containing protein. (334 aa)    
Predicted Functional Partners:
HSP90B1
Endoplasmin.
    
 0.437
ENSMMUP00000043660
Uncharacterized protein.
    
 0.437
TSC1
TSC complex subunit 1.
    
 0.436
TRAP1
Heat shock protein 75 kDa, mitochondrial.
    
 0.436
ENSMMUP00000063518
Uncharacterized protein.
    
 0.436
ENSMMUP00000074284
Uncharacterized protein.
    
 0.436
SLC29A1
HATPase_c domain-containing protein.
    
 0.436
HSP90AA1
HATPase_c domain-containing protein.
    
 0.436
HSPA9
Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family.
    
 0.432
SIRT5
NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Activates SHMT2 by mediating its desuccinyla [...]
   
 0.424
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.