STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASTLMetalloendopeptidase. (431 aa)    
Predicted Functional Partners:
MME
Membrane metalloendopeptidase.
      
 0.767
MMEL1
Membrane metalloendopeptidase like 1.
      
 0.689
SCN1B
Sodium voltage-gated channel beta subunit 1.
      
 0.628
APBA1
Amyloid beta precursor protein binding family A member 1.
      
 0.617
IDE
Uncharacterized protein; Belongs to the peptidase M16 family.
   
  
 0.614
CHRD
Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
   
 
 0.578
THOP1
Thimet oligopeptidase 1.
      
 0.540
BACE2
Beta-secretase 2; Belongs to the peptidase A1 family.
   
  
 0.538
RCC2
Regulator of chromosome condensation 2.
   
  
 0.489
INCA1
Inhibitor of CDK, cyclin A1 interacting protein 1.
      
 0.472
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.