STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSDHLSterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family. (373 aa)    
Predicted Functional Partners:
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
   
 0.993
MSMO1
C-4 methylsterol oxidase isoform 1; Belongs to the sterol desaturase family.
   
 0.991
SQLE
Squalene monooxygenase.
   
 
 0.973
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
 
 
 0.945
SC5D
Lathosterol oxidase; Belongs to the sterol desaturase family.
   
 0.931
DHCR7
7-dehydrocholesterol reductase.
   
 
 0.929
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
  
 0.919
FDFT1
Uncharacterized protein.
  
 
 0.913
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.843
IDI1
Isopentenyl-diphosphate delta isomerase 1.
   
 
 0.832
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.