STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DPPA3Uncharacterized protein. (159 aa)    
Predicted Functional Partners:
DPPA5
Developmental pluripotency associated 5.
   
  
 0.776
PRDM14
PR domain-containing protein 14.
      
 0.653
GDF3
Growth differentiation factor 3.
   
  
 0.650
POU5F1
POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency; Belongs to the POU transcription factor family. Class-5 subfamily.
   
 
 0.632
NANOG
Nanog homeobox.
      
 0.624
DAZL
Deleted in azoospermia like.
      
 0.618
PRDM1
PR/SET domain 1.
      
 0.602
ZP3
ZP domain-containing protein.
   
  
 0.596
DDX4
Putative ATP-dependent RNA helicase DDX4 isoform 1; Belongs to the DEAD box helicase family.
      
 0.594
TFCP2L1
Transcription factor CP2 like 1.
    
 
 0.572
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.