STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIX6SIX homeobox 6. (246 aa)    
Predicted Functional Partners:
OTX2
Orthodenticle homeobox 2.
   
 
 0.650
SPINK14
Serine peptidase inhibitor, Kazal type 14 (putative).
      
 0.600
LHX1
LIM homeobox 1.
    
 
 0.593
FAM92B
Family with sequence similarity 92 member B.
      
 0.589
AFAP1
Actin filament associated protein 1.
      
 0.582
PAX6
Uncharacterized protein.
   
 
 0.560
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
      
 0.547
VAX1
Ventral anterior homeobox 1.
   
 
 0.544
TMCO1
Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling; Belongs to the TMCO1 family.
      
 0.543
TMTC2
Transmembrane O-mannosyltransferase targeting cadherins 2.
    
 
 0.542
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.