Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but at higher resolution
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATR | BLM | ENSMMUP00000010409 | ENSMMUP00000025651 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | BLM RecQ like helicase. | 0.980 |
ATR | DNA2 | ENSMMUP00000010409 | ENSMMUP00000062574 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | DNA replication helicase/nuclease 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.851 |
ATR | ENSMMUP00000069269 | ENSMMUP00000010409 | ENSMMUP00000069269 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.916 |
ATR | FANCM | ENSMMUP00000010409 | ENSMMUP00000021700 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | FA complementation group M. | 0.997 |
ATR | RAD51 | ENSMMUP00000010409 | ENSMMUP00000033829 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | RAD51 recombinase; Belongs to the RecA family. | 0.882 |
ATR | RAD52 | ENSMMUP00000010409 | ENSMMUP00000024536 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | RAD52 homolog, DNA repair protein. | 0.917 |
ATR | RMI1 | ENSMMUP00000010409 | ENSMMUP00000066909 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | RecQ-mediated genome instability protein 1. | 0.681 |
ATR | TOP3A | ENSMMUP00000010409 | ENSMMUP00000017797 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.765 |
ATR | TP53 | ENSMMUP00000010409 | ENSMMUP00000011334 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.979 |
ATR | WRN | ENSMMUP00000010409 | ENSMMUP00000029828 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | WRN RecQ like helicase. | 0.998 |
BLM | ATR | ENSMMUP00000025651 | ENSMMUP00000010409 | BLM RecQ like helicase. | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | 0.980 |
BLM | DNA2 | ENSMMUP00000025651 | ENSMMUP00000062574 | BLM RecQ like helicase. | DNA replication helicase/nuclease 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.949 |
BLM | ENSMMUP00000069269 | ENSMMUP00000025651 | ENSMMUP00000069269 | BLM RecQ like helicase. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.943 |
BLM | FANCM | ENSMMUP00000025651 | ENSMMUP00000021700 | BLM RecQ like helicase. | FA complementation group M. | 0.998 |
BLM | RAD51 | ENSMMUP00000025651 | ENSMMUP00000033829 | BLM RecQ like helicase. | RAD51 recombinase; Belongs to the RecA family. | 0.990 |
BLM | RAD52 | ENSMMUP00000025651 | ENSMMUP00000024536 | BLM RecQ like helicase. | RAD52 homolog, DNA repair protein. | 0.964 |
BLM | RMI1 | ENSMMUP00000025651 | ENSMMUP00000066909 | BLM RecQ like helicase. | RecQ-mediated genome instability protein 1. | 0.999 |
BLM | TOP3A | ENSMMUP00000025651 | ENSMMUP00000017797 | BLM RecQ like helicase. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.999 |
BLM | TP53 | ENSMMUP00000025651 | ENSMMUP00000011334 | BLM RecQ like helicase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.751 |
BLM | WRN | ENSMMUP00000025651 | ENSMMUP00000029828 | BLM RecQ like helicase. | WRN RecQ like helicase. | 0.679 |
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