STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PROP1PROP paired-like homeobox 1. (234 aa)    
Predicted Functional Partners:
POU1F1
Pituitary-specific positive transcription factor 1; Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'.
    
 
 0.892
PRL
Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.
   
  
 0.762
GHRHR
Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.
   
  
 0.753
ART1
NAD(P)(+)--arginine ADP-ribosyltransferase.
   
  
 0.707
CRH
Corticotropin releasing hormone.
      
 0.687
RARA
Retinoic acid receptor alpha isoform 1.
      
 0.651
STAT3
Signal transducer and activator of transcription.
      
 0.637
CCDC189
Uncharacterized protein.
      
 0.612
ARMC3
Armadillo repeat containing 3.
      
 0.599
TMEM95
Transmembrane protein 95.
      
 0.582
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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