STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HES2Hes family bHLH transcription factor 2. (258 aa)    
Predicted Functional Partners:
FANCL
FA complementation group L.
    
 
 0.525
FANCF
Fanconi anemia group F protein.
    
 
 0.517
RBPJL
Recombination signal binding protein for immunoglobulin kappa J region like.
    
 0.512
RBPJ
Uncharacterized protein.
    
 0.512
FANCC
Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
    
   0.499
HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1 isoform a.
    
0.416
HEY2
Hairy/enhancer-of-split related with YRPW motif protein 2.
    
0.416
HEYL
Hes related family bHLH transcription factor with YRPW motif like.
    
0.416
ASCL2
Achaete-scute family bHLH transcription factor 2.
   
 
 0.402
ASCL1
Achaete-scute family bHLH transcription factor 1.
   
 
 0.402
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.