STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (320 aa)    
Predicted Functional Partners:
LDLR
Uncharacterized protein.
    
 0.989
AP2B1
AP complex subunit beta.
    
 0.899
DAB2
Differentially-expressed protein 2.
     
0.894
ITSN2
Intersectin 2.
    
 0.892
APOB
Apolipoprotein B.
     
 0.851
LRP2
LDL receptor related protein 2.
    
 0.848
LRP6
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.839
VLDLR
Very low density lipoprotein receptor.
    
 0.771
AP1B1
AP complex subunit beta.
    
 0.754
LRP4
Low-density lipoprotein receptor-related protein 4.
    
 0.735
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.