C11H12orf66 protein (Macaca mulatta) - STRING interaction network

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C11H12orf66

Chromosome 11 C12orf66 homolog. (566 aa)

Predicted Functional Partners:

KPTN

0.995

ITFG2

0.994

SZT2

0.990

YWHAH

0.977

WDR59

0.971

WDR24

0.969

NPRL2

0.969

BMT2

0.908

NPRL3

0.762

PPP1R3A

0.712

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMT2	C11H12orf66	ENSMMUP00000045316	ENSMMUP00000071588	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Chromosome 11 C12orf66 homolog.	0.908
BMT2	ITFG2	ENSMMUP00000045316	ENSMMUP00000009736	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Integrin alpha FG-GAP repeat containing 2.	0.910
BMT2	KPTN	ENSMMUP00000045316	ENSMMUP00000019318	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Kaptin, actin binding protein.	0.853
BMT2	NPRL2	ENSMMUP00000045316	ENSMMUP00000064708	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	NPR2 like, GATOR1 complex subunit.	0.854
BMT2	NPRL3	ENSMMUP00000045316	ENSMMUP00000000794	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Nitrogen permease regulator 3-like protein isoform 1.	0.812
BMT2	SZT2	ENSMMUP00000045316	ENSMMUP00000031173	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	SZT2 subunit of KICSTOR complex.	0.841
BMT2	WDR24	ENSMMUP00000045316	ENSMMUP00000058663	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	WD repeat domain 24.	0.446
BMT2	WDR59	ENSMMUP00000045316	ENSMMUP00000030899	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	WD repeat domain 59.	0.444
BMT2	YWHAH	ENSMMUP00000045316	ENSMMUP00000047869	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	DEP domain-containing protein.	0.873
C11H12orf66	BMT2	ENSMMUP00000071588	ENSMMUP00000045316	Chromosome 11 C12orf66 homolog.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.908
C11H12orf66	ITFG2	ENSMMUP00000071588	ENSMMUP00000009736	Chromosome 11 C12orf66 homolog.	Integrin alpha FG-GAP repeat containing 2.	0.994
C11H12orf66	KPTN	ENSMMUP00000071588	ENSMMUP00000019318	Chromosome 11 C12orf66 homolog.	Kaptin, actin binding protein.	0.995
C11H12orf66	NPRL2	ENSMMUP00000071588	ENSMMUP00000064708	Chromosome 11 C12orf66 homolog.	NPR2 like, GATOR1 complex subunit.	0.969
C11H12orf66	NPRL3	ENSMMUP00000071588	ENSMMUP00000000794	Chromosome 11 C12orf66 homolog.	Nitrogen permease regulator 3-like protein isoform 1.	0.762
C11H12orf66	PPP1R3A	ENSMMUP00000071588	ENSMMUP00000029810	Chromosome 11 C12orf66 homolog.	Protein phosphatase 1 regulatory subunit 3A.	0.712
C11H12orf66	SZT2	ENSMMUP00000071588	ENSMMUP00000031173	Chromosome 11 C12orf66 homolog.	SZT2 subunit of KICSTOR complex.	0.990
C11H12orf66	WDR24	ENSMMUP00000071588	ENSMMUP00000058663	Chromosome 11 C12orf66 homolog.	WD repeat domain 24.	0.969
C11H12orf66	WDR59	ENSMMUP00000071588	ENSMMUP00000030899	Chromosome 11 C12orf66 homolog.	WD repeat domain 59.	0.971
C11H12orf66	YWHAH	ENSMMUP00000071588	ENSMMUP00000047869	Chromosome 11 C12orf66 homolog.	DEP domain-containing protein.	0.977
ITFG2	BMT2	ENSMMUP00000009736	ENSMMUP00000045316	Integrin alpha FG-GAP repeat containing 2.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.910