STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TYRP1Tyrosinase related protein 1. (537 aa)    
Predicted Functional Partners:
DCT
Dopachrome tautomerase.
  
 
0.939
OCA2
OCA2 melanosomal transmembrane protein.
   
  
 0.921
SLC45A2
Solute carrier family 45 member 2.
   
 
 0.916
SLC24A5
Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
   
  
 0.880
TYR
Tyrosinase.
  
 
0.840
MLANA
Melanoma antigen recognized by T-cells 1.
   
  
 0.832
PMEL
Melanocyte protein PMEL isoform 3 preproprotein.
   
  
 0.794
GPNMB
PKD domain-containing protein.
      
 0.764
GPR143
G protein-coupled receptor 143.
   
 
 0.753
MITF
Microphthalmia-associated transcription factor isoform 1.
   
 
 0.746
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.