STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADGRA2Adhesion G protein-coupled receptor A2. (1348 aa)    
Predicted Functional Partners:
ADGRL1
Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.770
ADGRL3
Latrophilin-3; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.713
ADGRL2
Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.
   
 
 0.696
RECK
Reversion inducing cysteine rich protein with kazal motifs.
    
 0.628
TSPAN12
Tetraspanin.
      
 0.544
ADGRF1
Adhesion G protein-coupled receptor F1; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.535
ADGRF4
Adhesion G protein-coupled receptor F4; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.494
FZD4
Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.
   
  
 0.461
CTNNB1
Catenin beta-1.
   
 0.460
LRP6
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
   
 0.443
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.