STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKAP9A-kinase anchoring protein 9. (4049 aa)    
Predicted Functional Partners:
KCNQ1
Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.
    
 0.942
KCNE2
Potassium voltage-gated channel subfamily E regulatory subunit 2.
     
 0.815
PLD3
Phospholipase D family member 3.
    
 
 0.809
UNC5C
Unc-5 netrin receptor C.
      
 0.764
ADAM10
ADAM metallopeptidase domain 10.
   
  
 0.751
KCNE3
Uncharacterized protein.
     
 0.721
TREM2
Triggering receptor expressed on myeloid cells 2.
   
 
 0.718
CEP192
Centrosomal protein 192.
   
 0.697
PLK1
Serine/threonine-protein kinase PLK.
   
 0.674
APOE
Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]
   
 
 0.663
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (30%) [HD]