STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TREML2Triggering receptor expressed on myeloid cells like 2. (323 aa)    
Predicted Functional Partners:
TREML1
Uncharacterized protein.
 
 
 
 0.795
TREM2
Triggering receptor expressed on myeloid cells 2.
 
 
 
 0.774
TREM1
Triggering receptor expressed on myeloid cells 1.
 
 
 
 0.691
CD276
CD276 molecule.
   
  
 0.613
TYROBP
TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...]
   
 0.579
INPP5D
Inositol polyphosphate-5-phosphatase D.
    
 
 0.573
ASB10
Ankyrin repeat and SOCS box containing 10.
    
 0.559
CASS4
Cas scaffold protein family member 4.
   
 
 0.531
GPR65
Psychosine receptor; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.509
DEF8
Differentially expressed in FDCP 8 homolog.
   
  
 0.500
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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