STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1492 aa)    
Predicted Functional Partners:
XAB2
Pre-mRNA-splicing factor SYF1.
   
 0.996
PRPF19
Pre-mRNA processing factor 19.
    
 0.995
CRNKL1
Crooked neck pre-mRNA splicing factor 1.
    
 0.991
EFTUD2
116 kDa U5 small nuclear ribonucleoprotein component isoform a.
   
 0.986
RBM22
Pre-mRNA-splicing factor RBM22.
   
 0.986
BUD31
Protein BUD31 homolog.
   
 0.985
CDC5L
Cell division cycle 5-like protein.
   
 0.984
SNW1
SNW domain-containing protein 1.
   
 0.978
PPIE
Peptidylprolyl isomerase E.
    
 0.977
PRPF8
Pre-mRNA processing factor 8.
   
 0.977
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.