STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPG21SPG21 abhydrolase domain containing, maspardin. (510 aa)    
Predicted Functional Partners:
TECPR2
Tectonin beta-propeller repeat containing 2.
      
 0.651
SPG11
SPG11 vesicle trafficking associated, spatacsin.
      
 0.640
SPART
Spartin.
      
 0.626
ALDH16A1
Aldehyde dehydrogenase family 16 member A1.
      
 0.611
TNFSF15
Vascular endothelial cell growth inhibitor.
      
 0.572
CD58
Uncharacterized protein.
   
  
 0.564
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
   
  
 0.555
NIPA1
NIPA magnesium transporter 1.
      
 0.552
PAAF1
Proteasomal ATPase-associated factor 1.
      
 0.506
AP5Z1
Adaptor related protein complex 5 subunit zeta 1.
      
 0.499
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.