STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYLK3VPS35 retromer complex component. (1442 aa)    
Predicted Functional Partners:
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 0.999
VPS26A
Vacuolar protein sorting-associated protein 26A isoform 1.
   
 0.998
SNX2
Sorting nexin 2.
   
 0.993
SNX1
Uncharacterized protein.
   
 0.991
VPS26B
VPS26, retromer complex component B.
   
 0.991
SNX3
Sorting nexin-3 isoform a.
   
 0.984
SNX12
PX domain-containing protein.
   
 0.978
SNX5
Sorting nexin; Involved in several stages of intracellular trafficking.
   
 0.942
SNX6
Sorting nexin; Involved in several stages of intracellular trafficking.
   
 0.927
SNX27
Sorting nexin 27.
    
 0.911
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.