SLC29A1 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AR	ENSMMUP00000061388	ENSMMUP00000015004	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.	0.856
AKT1	CDC37	ENSMMUP00000061388	ENSMMUP00000066774	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cell division cycle 37.	0.981
AKT1	HSP90AA1	ENSMMUP00000061388	ENSMMUP00000080725	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	HATPase_c domain-containing protein.	0.997
AKT1	HSP90B1	ENSMMUP00000061388	ENSMMUP00000030897	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Endoplasmin.	0.939
AKT1	HSPA4	ENSMMUP00000061388	ENSMMUP00000051838	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Heat shock protein family A (Hsp70) member 4.	0.500
AKT1	HSPA8	ENSMMUP00000061388	ENSMMUP00000055649	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Heat shock cognate 71 kDa protein isoform 1; Belongs to the heat shock protein 70 family.	0.542
AKT1	SLC29A1	ENSMMUP00000061388	ENSMMUP00000075454	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	HATPase_c domain-containing protein.	0.992
AR	AKT1	ENSMMUP00000015004	ENSMMUP00000061388	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.856
AR	HSP90AA1	ENSMMUP00000015004	ENSMMUP00000080725	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.	HATPase_c domain-containing protein.	0.995
AR	HSP90B1	ENSMMUP00000015004	ENSMMUP00000030897	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.	Endoplasmin.	0.926
AR	HSPA1A	ENSMMUP00000015004	ENSMMUP00000072196	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.475
AR	HSPA4	ENSMMUP00000015004	ENSMMUP00000051838	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.	Heat shock protein family A (Hsp70) member 4.	0.625
AR	HSPA8	ENSMMUP00000015004	ENSMMUP00000055649	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.	Heat shock cognate 71 kDa protein isoform 1; Belongs to the heat shock protein 70 family.	0.409
AR	SLC29A1	ENSMMUP00000015004	ENSMMUP00000075454	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.	HATPase_c domain-containing protein.	0.986
CDC37	AKT1	ENSMMUP00000066774	ENSMMUP00000061388	Cell division cycle 37.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.981
CDC37	HSP90AA1	ENSMMUP00000066774	ENSMMUP00000080725	Cell division cycle 37.	HATPase_c domain-containing protein.	0.996
CDC37	HSP90B1	ENSMMUP00000066774	ENSMMUP00000030897	Cell division cycle 37.	Endoplasmin.	0.962
CDC37	HSPA4	ENSMMUP00000066774	ENSMMUP00000051838	Cell division cycle 37.	Heat shock protein family A (Hsp70) member 4.	0.583
CDC37	SLC29A1	ENSMMUP00000066774	ENSMMUP00000075454	Cell division cycle 37.	HATPase_c domain-containing protein.	0.996
CDC37	STIP1	ENSMMUP00000066774	ENSMMUP00000017002	Cell division cycle 37.	Uncharacterized protein.	0.902