STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VAPBVesicle-associated membrane protein-associated protein B/C isoform 1. (243 aa)    
Predicted Functional Partners:
STARD3
StAR-related lipid transfer protein 3; Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes (By similarity). Creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic reticulum via interaction with VAPA and VAPB (By similarity). Acts as a lipid transfer protein that redirects sterol to the endosome at the expense of the cell membrane and favors membrane formation inside endosomes (By similarity). May also mediate cholesterol transport between other membra [...]
    
 0.964
VAPA
MSP domain-containing protein.
  
0.963
ATF6
Activating transcription factor 6.
     
 0.935
SETX
Senataxin.
   
  
 0.785
OSBP
Oxysterol-binding protein; Belongs to the OSBP family.
   
 0.733
TARDBP
TAR DNA-binding protein 43.
   
 
 0.720
SNX2
Sorting nexin 2.
   
 
 0.690
FUS
Tripartite motif containing 72.
   
  
 0.679
ACBD5
Acyl-CoA binding domain containing 5.
    
 
 0.666
CHMP2B
Charged multivesicular body protein 2B.
      
 0.662
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.