CD59 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CD59

UPAR/Ly6 domain-containing protein. (194 aa)

Predicted Functional Partners:

CD46

0.939

CD55

0.932

CLUL1

0.730

SERPING1

0.717

C9

0.706

CLU

0.695

CFP

0.688

VTN

0.681

THBD

0.654

LOC722133

0.628

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C9	CD59	ENSMMUP00000026132	ENSMMUP00000077321	Complement C9.	UPAR/Ly6 domain-containing protein.	0.706
C9	CLU	ENSMMUP00000026132	ENSMMUP00000069256	Complement C9.	Clusterin; Belongs to the clusterin family.	0.693
C9	CLUL1	ENSMMUP00000026132	ENSMMUP00000041309	Complement C9.	Clusterin; Belongs to the clusterin family.	0.548
C9	VTN	ENSMMUP00000026132	ENSMMUP00000025171	Complement C9.	Uncharacterized protein.	0.863
CD46	CD55	ENSMMUP00000009336	ENSMMUP00000050092	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Uncharacterized protein.	0.650
CD46	CD59	ENSMMUP00000009336	ENSMMUP00000077321	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	UPAR/Ly6 domain-containing protein.	0.939
CD46	CFP	ENSMMUP00000009336	ENSMMUP00000041095	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Complement factor properdin.	0.638
CD46	CLU	ENSMMUP00000009336	ENSMMUP00000069256	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Clusterin; Belongs to the clusterin family.	0.447
CD46	CLUL1	ENSMMUP00000009336	ENSMMUP00000041309	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Clusterin; Belongs to the clusterin family.	0.522
CD46	LOC722133	ENSMMUP00000009336	ENSMMUP00000045849	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.632
CD46	SERPING1	ENSMMUP00000009336	ENSMMUP00000016570	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Serpin family G member 1; Belongs to the serpin family.	0.769
CD46	THBD	ENSMMUP00000009336	ENSMMUP00000022104	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Uncharacterized protein.	0.781
CD46	VTN	ENSMMUP00000009336	ENSMMUP00000025171	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Uncharacterized protein.	0.544
CD55	CD46	ENSMMUP00000050092	ENSMMUP00000009336	Uncharacterized protein.	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	0.650
CD55	CD59	ENSMMUP00000050092	ENSMMUP00000077321	Uncharacterized protein.	UPAR/Ly6 domain-containing protein.	0.932
CD55	CFP	ENSMMUP00000050092	ENSMMUP00000041095	Uncharacterized protein.	Complement factor properdin.	0.703
CD55	CLU	ENSMMUP00000050092	ENSMMUP00000069256	Uncharacterized protein.	Clusterin; Belongs to the clusterin family.	0.406
CD55	CLUL1	ENSMMUP00000050092	ENSMMUP00000041309	Uncharacterized protein.	Clusterin; Belongs to the clusterin family.	0.441
CD55	LOC722133	ENSMMUP00000050092	ENSMMUP00000045849	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.661
CD55	SERPING1	ENSMMUP00000050092	ENSMMUP00000016570	Uncharacterized protein.	Serpin family G member 1; Belongs to the serpin family.	0.662