STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGO2Shugoshin 2. (1258 aa)    
Predicted Functional Partners:
SGO1
Shugoshin 1.
  
  
 0.932
STAG3
SCD domain-containing protein.
     
 0.871
REC8
REC8 meiotic recombination protein.
     
 0.860
PLK1
Serine/threonine-protein kinase PLK.
   
 
 0.785
CAPZA3
F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
  
 0.784
ESPL1
Extra spindle pole bodies like 1, separase.
   
 
 0.753
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.745
NUDC
Nuclear migration protein nudC.
     
 0.709
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
 
 0.706
CDC20
Cell division cycle protein 20 homolog.
   
 
 0.703
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.