MCHR2 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNA14	GNAQ	ENSMMUP00000022417	ENSMMUP00000061851	G protein subunit alpha 14.	Guanine nucleotide-binding protein G(Q) subunit alpha.	0.965
GNA14	GNB1	ENSMMUP00000022417	ENSMMUP00000066781	G protein subunit alpha 14.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.977
GNA14	GNB2	ENSMMUP00000022417	ENSMMUP00000071351	G protein subunit alpha 14.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2.	0.972
GNA14	GNB3	ENSMMUP00000022417	ENSMMUP00000006868	G protein subunit alpha 14.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3.	0.967
GNA14	GNB4	ENSMMUP00000022417	ENSMMUP00000005459	G protein subunit alpha 14.	Guanine nucleotide-binding protein subunit beta-4.	0.977
GNA14	GNG4	ENSMMUP00000022417	ENSMMUP00000064430	G protein subunit alpha 14.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.971
GNA14	HCRT	ENSMMUP00000022417	ENSMMUP00000008448	G protein subunit alpha 14.	Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family.	0.427
GNA14	MCHR1	ENSMMUP00000022417	ENSMMUP00000022864	G protein subunit alpha 14.	Melanin-concentrating hormone receptor 1; Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.	0.780
GNA14	MCHR2	ENSMMUP00000022417	ENSMMUP00000078585	G protein subunit alpha 14.	Melanin-concentrating hormone receptor 2; Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis.	0.790
GNAQ	GNA14	ENSMMUP00000061851	ENSMMUP00000022417	Guanine nucleotide-binding protein G(Q) subunit alpha.	G protein subunit alpha 14.	0.965
GNAQ	GNB1	ENSMMUP00000061851	ENSMMUP00000066781	Guanine nucleotide-binding protein G(Q) subunit alpha.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.984
GNAQ	GNB2	ENSMMUP00000061851	ENSMMUP00000071351	Guanine nucleotide-binding protein G(Q) subunit alpha.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2.	0.972
GNAQ	GNB3	ENSMMUP00000061851	ENSMMUP00000006868	Guanine nucleotide-binding protein G(Q) subunit alpha.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3.	0.967
GNAQ	GNB4	ENSMMUP00000061851	ENSMMUP00000005459	Guanine nucleotide-binding protein G(Q) subunit alpha.	Guanine nucleotide-binding protein subunit beta-4.	0.984
GNAQ	GNG4	ENSMMUP00000061851	ENSMMUP00000064430	Guanine nucleotide-binding protein G(Q) subunit alpha.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.971
GNAQ	HCRT	ENSMMUP00000061851	ENSMMUP00000008448	Guanine nucleotide-binding protein G(Q) subunit alpha.	Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family.	0.432
GNAQ	MCHR1	ENSMMUP00000061851	ENSMMUP00000022864	Guanine nucleotide-binding protein G(Q) subunit alpha.	Melanin-concentrating hormone receptor 1; Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.	0.826
GNAQ	MCHR2	ENSMMUP00000061851	ENSMMUP00000078585	Guanine nucleotide-binding protein G(Q) subunit alpha.	Melanin-concentrating hormone receptor 2; Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis.	0.846
GNB1	GNA14	ENSMMUP00000066781	ENSMMUP00000022417	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	G protein subunit alpha 14.	0.977
GNB1	GNAQ	ENSMMUP00000066781	ENSMMUP00000061851	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	Guanine nucleotide-binding protein G(Q) subunit alpha.	0.984