STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECTIN4Nectin cell adhesion molecule 4. (514 aa)    
Predicted Functional Partners:
NECTIN1
Poliovirus receptor-related protein 1 isoform 1.
     
 
0.958
AFDN
Afadin, adherens junction formation factor.
     
 0.933
NECTIN3
Nectin cell adhesion molecule 3.
     
 
0.921
NECTIN2
Poliovirus receptor-related protein 2 isoform delta.
     
0.911
PARD3
Partitioning defective 3 homolog isoform 2.
     
  0.900
CD46
Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
     
 0.561
ANKRD22
Ankyrin repeat domain 22.
    
 0.461
MCAM
Uncharacterized protein.
  
  
  0.419
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.