STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMCR8SMCR8-C9orf72 complex subunit. (936 aa)    
Predicted Functional Partners:
WDR41
WD repeat domain 41.
   
 0.999
C15H9orf72
Uncharacterized protein.
   
 0.993
RAB8A
Ras-related protein Rab-8A.
    
 0.957
RAB39B
Ras-related protein Rab-39B.
    
 0.939
ULK1
Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
   
 0.930
ULK2
Unc-51 like autophagy activating kinase 2.
   
 0.923
TBK1
Serine/threonine-protein kinase TBK1.
   
 0.921
TANK
TRAF family member-associated NF-kappa-B activator isoform a.
   
 
 0.913
WDR1
WD repeat domain 1.
      
 0.870
FLCN
UDENN FLCN/SMCR8-type domain-containing protein.
      
 0.849
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.