STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOCS5Suppressor of cytokine signaling 5. (536 aa)    
Predicted Functional Partners:
JAK2
Tyrosine-protein kinase.
   
 0.967
ELOC
Elongin C; Belongs to the SKP1 family.
   
 0.946
CUL5
Cullin 5; Belongs to the cullin family.
   
 0.891
TYK2
Tyrosine-protein kinase.
    
 0.887
JAK1
Tyrosine-protein kinase.
    
 0.878
STAT1
Signal transducer and activator of transcription.
   
 0.856
STAT3
Signal transducer and activator of transcription.
   
 0.844
SOCS3
Suppressor of cytokine signaling 3.
     
 0.844
JAK3
Janus kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.843
STAT5A
Signal transducer and activator of transcription.
   
 0.832
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.