STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXO45F-box protein 45. (271 aa)    
Predicted Functional Partners:
MYCBP2
MYC binding protein 2.
    
 
 0.938
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.912
ENSMNEP00000042218
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.912
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.851
UBXN7
UBX domain-containing protein 7.
      
 0.740
WDR53
WD repeat domain 53.
      
 0.740
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.727
NCBP2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
      
 0.711
ELOC
Elongin C; Belongs to the SKP1 family.
    
 0.709
ENSMNEP00000045959
Uncharacterized protein.
    
 0.709
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.