STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IBTKInhibitor of Bruton tyrosine kinase. (1352 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
   
 0.798
IRAK1BP1
Interleukin 1 receptor associated kinase 1 binding protein 1.
      
 0.793
CUL1
Cullin 1; Belongs to the cullin family.
   
 0.742
CACUL1
CDK2 associated cullin domain 1; Belongs to the cullin family.
   
 0.674
BTK
Tyrosine-protein kinase.
   
 0.620
RANBP2
RAN binding protein 2.
   
 0.605
ANKRD9
Ankyrin repeat domain 9.
    
 0.560
WDYHV1
WDYHV motif containing 1.
      
 0.554
ABTB1
Ankyrin repeat and BTB domain containing 1.
    
0.497
APBA3
Amyloid beta precursor protein binding family A member 3.
      
 0.491
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.